product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-SIGLEC2 [4KB128]
catalog :
151339
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
29115
reactivity :
human
application :
FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-SIGLEC2 [4KB128]
Catalogue Number :
151339
Applications :
FACS
Antigen/Gene or Protein Targets :
Sialic acid binding Ig-like lectin 2 (SIGLEC2, CD22, BL-CAM)
Reactivity :
Human
Relevance :
SIGLEC-2 is first expressed in the cytomplasm of pre- and pro- B cells. SIGLEC-2 is broadly expressed in normal and neoplastic B cells and absent from other leucocytes and tissues. SIGLEC-2 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. SIGLEC-2 is strongly expressed in hairy cell leukaemias.
Host :
Mouse
Immunogen :
B cell lymphoma cells
Subclass :
IgG1 kappa
Myeloma Used :
P3/NS1/1-Ag4.1
Recommended Growing Conditions :
RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Research Area :
Cancer, Immunology, Stem Cell Biology
Notes :
Ultroser G can be used at 1% if the cells are not growing well.
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com