Anti-ATM [ATM 11G12] | Ximbio 151333 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ATM [ATM 11G12]

catalog :

151333

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

472

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-ATM [ATM 11G12]

Catalogue Number :

151333

Applications :

IF IP WB

Antigen/Gene or Protein Targets :

Ataxia Telangiesctasia Mutated (ATM)

Reactivity :

Human

Relevance :

The ATM protein is a member of the phosphatidylinositol-3 kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control. It is thought that the activation of ATM by autophosphorylation might be the initiating event of cellular responses to irradiation. The classic form of ataxia telangiectasia, an autosomal recessive cerebellar ataxia, results from the presence of two truncating ATM mutations, leading to a total loss of the ATM protein.

Host :

Mouse

Immunogen :

Residues 992-1144 of ATM fusion protein

Subclass :

IgG1

Molecular Weight (kDa) :

370

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

Suggested Dilution: 1:500

more info or order :

Ximbio product webpage