Anti-ASF1 [ASF 4A1/3] | Ximbio 151319 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ASF1 [ASF 4A1/3]

catalog :

151319

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25842

reactivity :

human, mouse

application :

western blot

more info or order :

Ximbio product webpage

product information

Name :

Anti-ASF1 [ASF 4A1/3]

Catalogue Number :

151319

Applications :

Antigen/Gene or Protein Targets :

Anti-Silencing Function 1 (ASF1)

Reactivity :

Human and Mouse

Relevance :

Anti-silencing function 1 (Asf1) belongs to the H3/H4 family of histone chaperones. Its function has not been fully elucidated but it is believed to be involved in ensuring a constant supply of histones at sites of nucleosome assembly. Asf1 interacts with the DNA damage checkpoint protein Rad53 and so may have a role in cell cycle regulation and DNA responses. ASF1 A and B (the two human subtypes) are the only known substrate for Tousled-like kinase (TLK). The Tousled kinases are themselves regulated by the checkpoint protein kinases involved in the DNA damage response.

Host :

Mouse

Immunogen :

FLAG-ASF1A

Subclass :

IgG2a

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

ASF 4A1/3 detects both ASF1A and ASF1B.

more info or order :

Ximbio product webpage