Anti-Plx [AZ44] | Ximbio 151301 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Plx [AZ44]

catalog :

151301

clonality :

monoclonal

host :

house mouse

conjugate :

nonconjugated

clone name :

380481

reactivity :

Xenopus laevis

application :

western blot, ELISA

more info or order :

Ximbio product webpage

product information

Name :

Anti-Plx [AZ44]

Catalogue Number :

151301

Applications :

ELISA WB

Antigen/Gene or Protein Targets :

Polo-like-kinase protein (Plk)

Synonyms :

Polo Like Kinase 1; Serine/Threonine-Protein Kinase 13; EC 2.7.11.21; STPK13; PLK-1; Cell Cycle Regulated Protein Kinase; Polo Like Kinase; EC 2.7.11

Reactivity :

Xenopus laevis

Relevance :

Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.

Host :

Mouse

Immunogen :

Baculo expressed Polo-like-kinase from Xenopus laevis

Subclass :

IgG1

Positive Control :

Xenopus egg extract

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Cell Type or Organelle Marker

Notes :

Plx is activated by phosphorylation. AZ44 only detects the mitotic form of Plx (Xenopus laevis) which may be due to the recognition of a phosphorylated epitope. Recommended concentration: 1ug/ml

more info or order :

Ximbio product webpage