product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-p53 [Pab DO-7]
catalog :
151293
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
7157
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, FACS
more info or order :
product information
Name :
Anti-p53 [Pab DO-7]
Catalogue Number :
151293
Applications :
ELISA FACS IHC IF WB
Antigen/Gene or Protein Targets :
p53 (N terminus)
Reactivity :
Human
Relevance :
p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. p53 is involved in many mechanisms of anticancer function, and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. Understanding the functions of mutant p53 can help in the development of new therapeutic approaches that may be useful in a broad range of cancer types.
Host :
Mouse
Subclass :
IgG2b
Positive Control :
MDA-MB-231 cell line
Molecular Weight (kDa) :
53
Recommended Growing Conditions :
DMEM + 5% FCS
Research Area :
Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling
Notes :
Immunocytochemistry (ICC) 1:20-1:200 Flow Cytometry (FACS) Assay Dependent Immunofluorescence (IF) 1:20-1:200 Immunohistochemistry (Paraffin) (IHC (P)) 1:100 - 200 Immunoprecipitation (IP) 1:50-1:100 Western Blot (WB) 1:50-1:200
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com