product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-HIF2A [EP190b]
catalog :
151263
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
124
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-HIF2A [EP190b]
Catalogue Number :
151263
Applications :
ELISA IHC WB
Antigen/Gene or Protein Targets :
Hypoxia-inducible factor 2, alpha subunit (HIF2A)
Reactivity :
Human
Relevance :
Induction of the Hif regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an important role in the growth of experimental tumours. HIF2A is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF1A has been observed in varying subsets of tumour cells from various solid tumours. HIF2A is also a potent activator of the tie2 gene, which is known to be selectively expressed in endothelial cells.
Host :
Mouse
Immunogen :
GST-human EPAS-1 (HIF2A) amino acids 535-631 fusion protein
Subclass :
IgG1
Myeloma Used :
P3/NS1/1-Ag4.1
Recommended Growing Conditions :
RPMI + 10% FCS + HAT
Strain :
Balb/c
Research Area :
Cancer, Cardiovascular, Epigenetics & Nuclear Signalling, Metabolism
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com