Anti-MUC18 [OJ79c MUC 18] | Ximbio 151214 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MUC18 [OJ79c MUC 18]

catalog :

151214

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4162

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-MUC18 [OJ79c MUC 18]

Catalogue Number :

151214

Applications :

FACS IHC IF

Antigen/Gene or Protein Targets :

MUC18 (CD146)

Synonyms :

ADMCKD, ADMCKD1, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227

Reactivity :

Human

Relevance :

CD146 has been identified as a cell adhesion molecule and is useful in differential diagnosis of certain lesions including melanomas and various types of gestational trophoblastic lesions. It is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Host :

Mouse

Immunogen :

Recombinant MUC18 (D1-D5) Fc chimeric protein

Subclass :

IgG1 kappa

Positive Control :

A-375 cell, SK-MEL-24 cell, HUV-EC or HeLa cell lysates. Tonsil or Melanoma.

Molecular Weight (kDa) :

130kDa

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

RPMI + 10% FCS + HAT

Research Area :

Adhesion, Cancer, Cardiovascular, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

Notes :

Cellular Localization: Cell surface Suggested Dilutions: Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1.0ug/ml);

more info or order :

Ximbio product webpage