Anti-SIGLEC1 [HSn 7D2] | Ximbio 151199 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-SIGLEC1 [HSn 7D2]

catalog :

151199

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6614

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, FACS, radioimmunoassay

more info or order :

Ximbio product webpage

product information

Name :

Anti-SIGLEC1 [HSn 7D2]

Catalogue Number :

151199

Applications :

ELISA FACS IHC RIA WB

Antigen/Gene or Protein Targets :

Sialoadhesin domains 1-4 (SIGLEC1)

Synonyms :

CD169, Sialoadhesin 1

Reactivity :

Human

Relevance :

The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.

Host :

Mouse

Immunogen :

Fc fusion protein containing N-terminal 4 domains of human sialoadhesin.

Subclass :

IgG1

Positive Control :

Human spleen (IHC), human peripheral blood monocytes (FACS) or MCF7 cells (IF)

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Adhesion, Cancer, Immunology

Notes :

HSn 7D2 is recommended for cryostat sections and will stain paraffin sections after protease treatment. Detailed procedures for de-paraffinisation are contained in the Steiniger paper.

more info or order :

Ximbio product webpage