Anti-CyclinB1 [V92.1] | Ximbio 151180 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CyclinB1 [V92.1]

catalog :

151180

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

891

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-CyclinB1 [V92.1]

Catalogue Number :

151180

Applications :

FACS IHC IF IP WB

Antigen/Gene or Protein Targets :

Cyclin B1

Synonyms :

CCNB, CCNB1, CCNB1_HUMAN, G2 Mitotic Specific Cyclin B1 Human Entrez Gene ID 891 Human SwissProt P14635 Human Unigene 23960 Human Gene Symbol CCNB1 Human Chromosome Location 5q13.2

Reactivity :

Hamster, Human and Mouse

Relevance :

Clone V92.1, recognizes a protein of 55-62kDa, identified as cyclin B1. Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin B1 is a marker of cell proliferation and a key component of the cell cycle progression machinery. Cyclin B1 may prove to be a prognostic marker in neoplasia. V92.1 may be used to immunoprecipitate active CDK1/cyclin complexes.

Host :

Mouse

Immunogen :

Hamster Cyclin B1

Subclass :

IgG1 kappa

Positive Control :

Cell line in logarithmic growth phase. Tonsil or testicular, endometrial, prostate or ovarian carcinoma.

Molecular Weight (kDa) :

55-62kDa

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

Notes :

Cellular Localization: Cytoplasmic Suggwested Dilutions: Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1ug/ml); Immunoprecipitation (1-2ug/500ug protein) (precipitates active CDK1/cyclin B1 complexes);

more info or order :

Ximbio product webpage