Anti-CD3 [UCH-T1®] | Ximbio 151175 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-CD3 [UCH-T1®]

catalog :

151175

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

912

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, radioimmunoassay

more info or order :

Ximbio product webpage

product information

Name :

Anti-CD3 [UCH-T1®]

Catalogue Number :

151175

Applications :

FACS IHC IF IP Fn RIA WB

Antigen/Gene or Protein Targets :

CD3

Synonyms :

T3 complex

Reactivity :

Human

Relevance :

The CD3 complex, composed of five CD3 polypeptide chains, associates with the T cell antigen receptor (TCR) and is found on all mature human T lymphocytes. UCH-T1 is considered a pan T-cell marker - it can be used for the detection of T cell populations in peripheral blood and lymph nodes and the categorisation of T versus B cell lymphomas and leukaemias. It reacts with the majority of peripheral blood T lymphocytes, a major proportion of thymocytes, the majority of T cell chronic lymphocytic leukaemia cells, Sézary leukaemias and approximately 70% of acute lymphoblastic leukaemias of T cell origin. It can also be used to study the role of CD3 in TCR signal transduction events.

Host :

Mouse

Immunogen :

Human infant thymocytes and Sezary cells.

Subclass :

IgG1

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

RPMI 1640 + 5% FCS.

Strain :

Balb/c

Research Area :

Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

Notes :

Recommended for the enrichment of T cell populations by cell sorting or panning.

more info or order :

Ximbio product webpage