Anti-Rb1 [Rb1 (1F8)] | Ximbio 151156 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Rb1 [Rb1 (1F8)]

catalog :

151156

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5925

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Rb1 [Rb1 (1F8)]

Catalogue Number :

151156

Applications :

IHC IF IP

Antigen/Gene or Protein Targets :

Retinoblastoma (Rb1)

Reactivity :

Human

Relevance :

The Retinoblastoma protein (Rb) is a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.

Host :

Mouse

Immunogen :

Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 and representing 283 mino acids of Human Rb cDNA

Subclass :

IgG1

Molecular Weight (kDa) :

105

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 10% FCS.

Strain :

Balb/c

Research Area :

Cancer, Cell Cycle, Cell Type or Organelle Marker

Notes :

Rb1 may be used in sensitive assays for Rb complexed to the T antigen

more info or order :

Ximbio product webpage