Anti-PCNA [PC8] | Ximbio 151151 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PCNA [PC8]

catalog :

151151

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3054

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-PCNA [PC8]

Catalogue Number :

151151

Applications :

IHC IP WB

Antigen/Gene or Protein Targets :

Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein

Synonyms :

Proliferating Cell Nuclear Antigen; DNA Polymerase Delta Auxiliary Protein; ATLD2

Reactivity :

Human, Schizosaccharomyces pombe and Saccharomyces frugiperda

Relevance :

PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis).

Host :

Mouse

Immunogen :

Protein A-PCNA fusion obtained from pC2T.

Subclass :

IgG3

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

RPMI 1640 + 5% FCS.

Research Area :

Cancer, Cell Cycle, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling

Notes :

The PCNA Epitope also found in Schizosaccharomyces pombe (yeast) and Spodoptera frugiperda (insect) in addition to man. PC8 is recommended for use on formalin-fixed paraffin embedded sections.

more info or order :

Ximbio product webpage