Anti-PCNA [PC5] | Ximbio 151150 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-PCNA [PC5]

catalog :

151150

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3054

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-PCNA [PC5]

Catalogue Number :

151150

Applications :

IHC WB

Antigen/Gene or Protein Targets :

Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein

Synonyms :

Proliferating Cell Nuclear Antigen; DNA Polymerase Delta Auxiliary Protein; ATLD2

Reactivity :

Human, Insect and Schizosaccharomyces pombe

Relevance :

PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis).

Host :

Mouse

Immunogen :

Protein A-PCNA fusion obtained from pC2T.

Subclass :

IgG1 kappa

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 10% FCS

Research Area :

Cancer, Cell Cycle, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage