product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-PCNA [PC11]
catalog :
151149
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3054
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
Ximbio product webpage
product information
Name :
Anti-PCNA [PC11]
Catalogue Number :
151149
Applications :
IHC WB
Antigen/Gene or Protein Targets :
Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein.
Synonyms :
Proliferating Cell Nuclear Antigen; DNA Polymerase Delta Auxiliary Protein; ATLD2
Reactivity :
Human and Schizosaccharomyces pombe
Relevance :
PCNA, also known as polymerase delta auxiliary protein, is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumour tissue (i.e. relevant to prognosis).
Host :
Mouse
Immunogen :
Protein A-PCNA fusion obtained from pC2T.
Subclass :
IgG1
Myeloma Used :
Sp2/0-Ag14
Recommended Growing Conditions :
DMEM + 5% FCS
Research Area :
Cancer, Cell Cycle, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com