Anti-p53 [Pab DO-1] | Ximbio 151147 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-p53 [Pab DO-1]

catalog :

151147

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7157

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-p53 [Pab DO-1]

Catalogue Number :

151147

Applications :

ChIP IHC IF IP WB

Antigen/Gene or Protein Targets :

p53 (N terminus)

Synonyms :

P53, Trp53, pantropic

Reactivity :

Human

Relevance :

p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. p53 is involved in many mechanisms of anticancer function, and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. Understanding the functions of mutant p53 can help in the development of new therapeutic approaches that may be useful in a broad range of cancer types.

Host :

Mouse

Immunogen :

Recombinant human wild type p53 protein expressed in E.coli

Subclass :

IgG2a

Positive Control :

MDA-MB-231 cell line

Molecular Weight (kDa) :

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

Epitope maps between amino acid residues 11-25 of p53 of human origin

more info or order :

Ximbio product webpage