Anti-p53 [Pab 240] | Ximbio 151146 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-p53 [Pab 240]

catalog :

151146

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7157

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-p53 [Pab 240]

Catalogue Number :

151146

Applications :

FACS IHC IF IP WB

Antigen/Gene or Protein Targets :

p53

Reactivity :

Chicken and Mammalian

Relevance :

p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas.

Host :

Mouse

Immunogen :

A gel purified p53-b-galactosidase fusion protein containing p53 sequence from amino acids 14-389 (derived from the pSV53C p53 cDNA clone)

Subclass :

IgG1 kappa

Positive Control :

MDA-MB-231 cell line

Molecular Weight (kDa) :

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

RPMI 1640 + 7.5% FCS

Strain :

Balb/c

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

Detection of p53 using PAb 240: 50% colon cancer sections are positive, 30% of breast cancer sections and 70% of lung cancer sections. Normal and premalignant tissue are negative.

more info or order :

Ximbio product webpage