Anti-p53 [Pab 1802] | Ximbio 151145 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-p53 [Pab 1802]

catalog :

151145

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7157

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-p53 [Pab 1802]

Catalogue Number :

151145

Applications :

ELISA IHC IP WB

Antigen/Gene or Protein Targets :

p53

Synonyms :

Tumor Protein P53; Phosphoprotein P53; Antigen NY-CO-13; P53; Transformation-Related Protein 53; Mutant Tumor Protein 53; Li-Fraumeni Syndrome; P53 Tumor Suppressor; Tumor Suppressor P53; TRP53; BCC7; LFS1

Reactivity :

Human and Mouse

Relevance :

p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. PAB 1802 may be used to show the expression of human p53 cDNA in cos-l cells.

Host :

Mouse

Immunogen :

P53-beta galactosidase fusion protein

Subclass :

IgG1

Positive Control :

MDA-MB-231 cell line

Molecular Weight (kDa) :

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, DNA Damage and Repair, Epigenetics & Nuclear Signalling

Notes :

PAB 1802 cross reacts with the murine epitope in C-terminal region between residues 306-393 in both wild type & mutant forms.

more info or order :

Ximbio product webpage