Anti-Integrin a2bb3 [P256] | Ximbio 151138 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin a2bb3 [P256]

catalog :

151138

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3655

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin a2bb3 [P256]

Catalogue Number :

151138

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

Integrin a2bß3 (CD41 & CD61)

Synonyms :

alpha 2B/beta3, alphaIIbetabeta3, GPIIbetabeta3, CD41/CD61, platelet fibronectin receptor

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of a and ß subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin a2b (CD41) and integrin ß3 (CD61) associate to form the heterodimer integrin a2bb3 (CD41/CD61; GPIIb/IIIa), a fibronectin receptor expressed in platelets. P256 has potential use for imaging of thrombi. P256 induces aggregation of normal platelets in plasma.

Host :

Mouse

Immunogen :

Peripheral blood mononuclear cells

Subclass :

IgG1

Molecular Weight (kDa) :

135

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Cancer

more info or order :

Ximbio product webpage