Anti-Integrin a6 [MP4F10] | Ximbio 151134 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin a6 [MP4F10]

catalog :

151134

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3655

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin a6 [MP4F10]

Catalogue Number :

151134

Applications :

FACS IHC IP

Antigen/Gene or Protein Targets :

Integrin alpha6 (CD49f)

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha 6 is found on epithelial and endothelial basement membranes and colorectal carcinoma. Integrin alpha 6 associates with integrin beta 4 to form integrin a6b4, one of the most abundant keratinocyte integrins, and binds laminin. MP 4F10 may be used in clinical studies for tumour grading as it will stain both moderately and well-differentiated colorectal adenocarcinoma.

Host :

Mouse

Immunogen :

SW1222 human colorectal cell line.

Subclass :

IgG2b

Myeloma Used :

P3/NS1/1-Ag4.1

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Adhesion, Developmental Biology, Stem Cell Biology

more info or order :

Ximbio product webpage