Anti-Integrin b3 [MHF4] | Ximbio 151133 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin b3 [MHF4]

catalog :

151133

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3655

reactivity :

human, rat

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin b3 [MHF4]

Catalogue Number :

151133

Applications :

FACS IHC IF IP

Antigen/Gene or Protein Targets :

Integrin ß3 chain (CD61)

Reactivity :

Human and Rat

Relevance :

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin b3 is expressed in osteoclasts, megacaryocytes and platelets. MHF4 may be used to identify osteoclasts in tissue sections and bone cell suspensions. The MHF4 epitope is different to the F11 epitope.

Host :

Mouse

Immunogen :

A bone cell suspension containing osteoclasts, osteoblasts and bone marrow cells obtained from the long bones of newborn Sprague Dawley rats.

Subclass :

IgG1

Molecular Weight (kDa) :

118/100

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Adhesion, Cardiovascular, Cell Signaling & Signal Transduction

Notes :

A heterodimeric molecule with a characteristic shift in apparent molecular mass on reduction (137/78 kDa nonreduced; 118/100 kDa reduced).

more info or order :

Ximbio product webpage