product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-Keratin8 [LP3K]
catalog :
151126
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3856
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
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product information
Name :
Anti-Keratin8 [LP3K]
Catalogue Number :
151126
Applications :
IHC IF WB
Antigen/Gene or Protein Targets :
Keratin 8
Reactivity :
Human
Relevance :
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. Keratin 8 is the tissue polypeptide antigen (TPA) reported to be present in the serum of cancer patients.
Host :
Mouse
Immunogen :
Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes.
Subclass :
IgG1
Molecular Weight (kDa) :
52
Myeloma Used :
Sp2/0-Ag14
Recommended Growing Conditions :
DMEM + 5% FCS
Strain :
Balb/c
Research Area :
Cell Signaling & Signal Transduction
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company information
Ximbio
enquiries@ximbio.com
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