Anti-Keratin 5/6/18 [LP34] | Ximbio 151125 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Keratin 5/6/18 [LP34]

catalog :

151125

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3848

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

more info or order :

Ximbio product webpage

product information

Name :

Anti-Keratin 5/6/18 [LP34]

Catalogue Number :

151125

Applications :

ELISA IHC IF WB

Antigen/Gene or Protein Targets :

Keratin 5/6/18 (pan-epithelial)

Reactivity :

Human

Relevance :

Keratins 5, 6 are members of type II keratins family that are specifically expressed in the inner root sheath of hair follicles. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin 18 is memeber of the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. Anti-Keratin 5/6/18 [LP34] shows a broad pattern of reactivity with human epithelial tissues, from simple glandular epithelia to stratified squamous epithelia. Epithelial cells are labelled whether they are ectodermal, mesodermal, or endodermal in origin. However, the recognition of cytokeratin 18 on paraffin sections using this antibody may be variable.

Host :

Mouse

Immunogen :

Detergent-insoluble fraction of psoriatic human epidermis

Subclass :

IgG1

Positive Control :

Human skin

Molecular Weight (kDa) :

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage