Anti-Keratin16 [LL025] | Ximbio 151123 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Keratin16 [LL025]

catalog :

151123

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3868

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Keratin16 [LL025]

Catalogue Number :

151123

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

Keratin 16

Reactivity :

Human

Relevance :

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 16 is expressed in suprabasal keratinocytes of wounded epidermis. Keratin 16 suprabasal expression is found in situations of high cell turnover. LL025 reactivity was completely negative in normal breast tissue and non-invasive breast carcinoma. However, 10% of the invasive carcinomas tested were diffusely or focally positive with this antibody.

Host :

Mouse

Immunogen :

A synthetic peptide corresponding to an amino acid sequence of the carboxyl terminus of human keratin 16.

Subclass :

IgG1

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cell Signaling & Signal Transduction

Notes :

Immunoperoxidase is recommended for use on frozen sections.

more info or order :

Ximbio product webpage