Anti-MCSP [LHM 2] | Ximbio 151118 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-MCSP [LHM 2]

catalog :

151118

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9450

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-MCSP [LHM 2]

Catalogue Number :

151118

Applications :

FACS IHC IF IP WB

Antigen/Gene or Protein Targets :

Melanoma associated Chondroitin Sulphate Proteoglycan (MCSP or NG2)

Reactivity :

Human

Relevance :

The LHM2 antibody is a very good marker for melanoma (>90% stained). LHM2 also stains basal cell carcinomas and subpopulation of basal keratinocytes. LHM2 can be used as a diagnostic panel for immunopathology of malignant melanoma and potential candidates for immunoimaging and immunotherapy of disseminated melanoma. The originators of this antibody report that the MCSP is a cell surface marker specific for epidermal stem cells (J. Invest. Dermatol. in press). Potential applications of the LHM2 antibody include use for separation/isolation of epidermal stem cells, detection of stem cells in skin biopsies or epithelial cell cultures and optimisation of culture conditions to retain epidermal stem cell population in in vitro cultures.

Host :

Mouse

Immunogen :

A 375P cells crude extract.

Subclass :

IgG1 kappa

Molecular Weight (kDa) :

240

Myeloma Used :

NS0

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Adhesion, Cancer, Cell Type or Organelle Marker, Neurobiology

more info or order :

Ximbio product webpage