Anti-Keratin7,13,17 & 18 [LdS 23] | Ximbio 151114 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Keratin7,13,17 & 18 [LdS 23]

catalog :

151114

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3848

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-Keratin7,13,17 & 18 [LdS 23]

Catalogue Number :

151114

Applications :

IHC IF IP WB

Antigen/Gene or Protein Targets :

Keratin 7,13,17 & 18

Reactivity :

Human

Relevance :

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. Keratin 17 is expressed in suprabasal keratinocytes of wounded epidermis. Keratins 8 and 18 are two of the first keratins expressed in the embryo, and persist into adult tissues as the keratin pair representing minimal epithelial keratin expression. Keratins 8 and 18 are major components of all simple epithelia (but not of stratified squamous epithelia) and adenocarcinomas. LdS 23 is useful for studies of epithelial cells and tumour origin.

Host :

Mouse

Immunogen :

Cytoskeletons of the human urothelial RT4 cell line

Subclass :

IgG1

Recommended Growing Conditions :

DMEM + 5% FCS

Research Area :

Cell Signaling & Signal Transduction

more info or order :

Ximbio product webpage