Anti-Integrin a3 [IA3] | Ximbio 151109 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin a3 [IA3]

catalog :

151109

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3655

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin a3 [IA3]

Catalogue Number :

151109

Applications :

FACS IHC IF Fn

Antigen/Gene or Protein Targets :

Integrin a3 (CD49c)

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of a and ß subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin a3 is found on most cell types. Integrin a3 associates with b1 integrin to form integrin a3b1, which is one of the most abundant keratinocyte integrins and binds laminin 5. IA3 is useful for studies on inhibition of cell-cell adhesion and cell-substrate adhesion.

Host :

Mouse

Immunogen :

Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant.

Subclass :

IgG1

Myeloma Used :

P3X63Ag8.653

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Adhesion, Cancer

more info or order :

Ximbio product webpage