Anti-APC [Ali 12-28] | Ximbio 151073 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-APC [Ali 12-28]

catalog :

151073

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1277

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-APC [Ali 12-28]

Catalogue Number :

151073

Applications :

ELISA IHC IF IP WB

Antigen/Gene or Protein Targets :

Adenomatous Polyposis Coli (APC)

Reactivity :

Human

Relevance :

The adenomatous polyposis coli (APC) tumour suppressor gene is mutated (often by deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and in over 80% of colorectal cancers. Ali 12-28 may be used for the detection of APC expression and APC mutations.

Host :

Mouse

Immunogen :

N-terminal APC-MBP fusion protein

Subclass :

IgG1

Positive Control :

Cancer cell lines: SW480, LOVO, DLD1, SW837

Molecular Weight (kDa) :

310

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Cancer, Cardiovascular, Cell Cycle, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Neurobiology, Stem Cell Biology

Notes :

Ali 12-28 detects both normal and mutant-truncated forms of the APC. Recommended concentrations for western blot: 4 µg/ml Immunofluorescence: 20 µg/ml

more info or order :

Ximbio product webpage