product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-BCRABL [7c6]
catalog :
151062
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
25
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Ximbio product webpage
product information
Name :
Anti-BCRABL [7c6]
Catalogue Number :
151062
Applications :
IF IP WB
Antigen/Gene or Protein Targets :
BCRABL
Reactivity :
Human
Relevance :
The BCR gene is involved in the 9:22 translocation that generates the Philadelphia chromosome both in chronic myeloid leukemia (CML) and in a proportion of cases of acute lymphocytic leukemia (ALL). A 5' bcr sequence becomes fused to an abl sequence (including tyrosine kinase domain sequences) from chromosome 9 and results in the production of a chimaeric BCR-ABL protein with enhanced kinase activity. These antibodies may be useful for studies of the oncogene and have potential diagnostic and prognostic applications.
Host :
Mouse
Immunogen :
Bcr686 thyroglobulin conjugate
Subclass :
IgG2a
Molecular Weight (kDa) :
210
Myeloma Used :
P3X63Ag8
Recommended Growing Conditions :
DMEM + 5% FCS
Strain :
Balb/c
Research Area :
Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com