product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-S100A8 & S100A9 [5.5]
catalog :
151056
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6280
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, FACS
more info or order :
product information
Name :
Anti-S100A8 & S100A9 [5.5]
Catalogue Number :
151056
Applications :
ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets :
S100A8 (MRP-8) & S100A9 (MRP-14)
Reactivity :
Human
Relevance :
S100A8 (MRP-8) and S100A9 (MRP-14) are cytosolic calcium-binding proteins of 8kDa and 14kDa that form a heterodimer. S100A8 and S100A9 are expressed in secretory and inflamed keratinocytes, peripheral blood monocytes, neutrophils and has been described in platelets, dendritic cells and some T cell types. Expression is lost on tissue maturation of monocytes to macrophages. S100A9 may be associated with monocyte and neutrophil activation and the accumulation of these cells in inflammatory sites.
Host :
Mouse
Immunogen :
Acute monocytic leukaemia cells.
Subclass :
IgG1
Positive Control :
This antibody was used to detect S100A8/S100A9 in neutrophil extracts (Hogg et al., 1989) This antibody was used to detect S100A8/S100A9 in Human monocyte and neutrophil extracts (Edgeworth et al., 1991)
Recommended Growing Conditions :
DMEM + 5% FCS
Research Area :
Cell Cycle, Epigenetics & Nuclear Signalling
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com