Anti-ERCC1 [ERCC1 3H11] | Ximbio 151050 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-ERCC1 [ERCC1 3H11]

catalog :

151050

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2067

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Ximbio product webpage

product information

Name :

Anti-ERCC1 [ERCC1 3H11]

Catalogue Number :

151050

Applications :

IF IP WB

Antigen/Gene or Protein Targets :

ERCC1

Reactivity :

Human

Relevance :

Nucleotide excision repair (NER) is a DNA repair pathway that removes lesions induced by a variety of agents such as UV irradiation. ERCC1 binds to XPF to form the heterodimer ERCC1-XPF, which is a DNA endonuclease that is essential for the dual incision step of NER (cleaves 5' of the DNA lesion). Some publications report that ERCC1 is elevated in cisplatin-resistant cells.

Host :

Mouse

Immunogen :

Full length HIS-tagged recombinant human ERCC1

Subclass :

IgG2a

Positive Control :

A431 cells or HeLa

Molecular Weight (kDa) :

33-36

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Cancer, DNA Damage and Repair, Epigenetics & Nuclear Signalling

more info or order :

Ximbio product webpage