product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-CD45R [351C5]
catalog :
151047
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
52
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
Ximbio product webpage
product information
Name :
Anti-CD45R [351C5]
Catalogue Number :
151047
Applications :
FACS IHC IF IP WB
Antigen/Gene or Protein Targets :
Protein tyrosine phosphatase, receptor type, C (PTPRC, CD45R)
Synonyms :
Protein Tyrosine Phosphatase; Receptor Type C; CD45 Antigen; CD45; L-CA; T200; Protein Tyrosine Phosphatase; Receptor Type; C Polypeptide; T200 Leukocyte Common Antigen; T200 Glycoprotein; EC 3.1.3.48; GP180; CD45R; B220; LCA; LY5
Reactivity :
Human
Relevance :
PTPRC (CD45) is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45R and CD45RO are two of multiple PTPRC isoforms generated by alternative splicing. CD45R is found on B lymphocyte and T lymphocyte subsets. CD45RO is present on 50% of T cells, most granulocytes and monocytes and most mature T cell tumours. 351C5 may be used in the typing of leukaemias and lymphomas and in studies of functional subsets of B and T cells.
Host :
Mouse
Immunogen :
Raji cells
Subclass :
IgM
Recommended Growing Conditions :
DMEM + 5% FCS
Research Area :
Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology
more info or order :
Ximbio product webpage
company information
Ximbio
enquiries@ximbio.com
ximbio.com