Anti-Integrin aX [3.9] | Ximbio 151044 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin aX [3.9]

catalog :

151044

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3687

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin aX [3.9]

Catalogue Number :

151044

Applications :

FACS IHC IF IP Fn

Antigen/Gene or Protein Targets :

Integrin alpha X (CD11c; gp150/95 a subunit)

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha X is found on hairy cell leukaemias, malignant histiocytes, on tissue macrophages, monocytes, activated neutrophils and some T-cell clones.

Host :

Mouse

Immunogen :

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Subclass :

IgG1

Positive Control :

Peripheral blood monocytes (PBMCs) (FACS), Uterine tissue sections (IHC)

Molecular Weight (kDa) :

150

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

DMEM + 5% FCS

Strain :

Balb/c

Research Area :

Adhesion, Cell Signaling & Signal Transduction, Immunology, Stem Cell Biology

Notes :

Shown to inhibit adhesion in Jawhara et al., 2012. For FACS: 1ug per 1x10^6 cells

more info or order :

Ximbio product webpage