Anti-Integrins aL, aX, aMb2 [24] | Ximbio 151040 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrins aL, aX, aMb2 [24]

catalog :

151040

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3655

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, radioimmunoassay

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrins aL, aX, aMb2 [24]

Catalogue Number :

151040

Applications :

FACS IHC IF IP RIA WB

Antigen/Gene or Protein Targets :

Activation epitope on integrin beta 2(CD18) subunit

Synonyms :

Integrin Subunit Alpha L; Leukocyte Function-Associated Molecule 1 Alpha Chain; CD11 Antigen-Like Family Member A; Antigen CD11A (P180); LFA-1A; CD11A; Antigen CD11A (P180); Lymphocyte Function-Associated Antigen 1; Lymphocyte Function-Associated Antigen 1; Alpha Polypeptide; Integrin Gene Promoter; Alpha Polypeptide; Integrin Alpha L; CD11a Antigen; LFA-1; LFA1A

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1), integrin alpha M (CD11b) to form Complement Receptor 3 (CR3), integrin alpha X (CD11c) to form Complement Receptor 4 (CR4) and with CD11d to form p150,95. Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs) and matrix molecules. Clone 24 may be used as a reporter of the activation state of the CD11/CD18 integrins and can also be induced following exposure with Mg2+ or Mn2+.

Host :

Mouse

Immunogen :

Fibronectin-purified human monocytes .

Subclass :

IgG1

Positive Control :

Tonsil

Molecular Weight (kDa) :

95 & 180

Myeloma Used :

Sp2/0-Ag14

Recommended Growing Conditions :

E4 + 10% FCS

Strain :

Balb/c

Research Area :

Adhesion

Notes :

CD18: 95 kDa, CD11: 180kDa

more info or order :

Ximbio product webpage