Anti-Integrin aV [13C2] | Ximbio 151032 product information

product summary

company name :

Ximbio

product type :

antibody

product name :

Anti-Integrin aV [13C2]

catalog :

151032

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3685

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, FACS

more info or order :

Ximbio product webpage

product information

Name :

Anti-Integrin aV [13C2]

Catalogue Number :

151032

Applications :

FACS IHC IP

Antigen/Gene or Protein Targets :

Integrin alpha V (CD51)

Reactivity :

Human

Relevance :

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha V associates with integrin beta3 to form the osteoclast functional antigen (vitronectin receptor). Integrin alpha V is found in osteoclasts, placenta, melanoma cell lines and some epithelial cell lines. Expression of integrin alpha V increases with melanoma progression.

Host :

Mouse

Immunogen :

A cell suspension containing osteoclasts from osteoclastomas.

Subclass :

IgG1

Myeloma Used :

P3X63Ag8

Recommended Growing Conditions :

DMEM + 5% FCS.

Strain :

Balb/c

Research Area :

Stem Cell Biology

more info or order :

Ximbio product webpage