product summary
company name :
Ximbio
product type :
antibody
product name :
Anti-FCGR1 [10.1]
catalog :
151026
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2209
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS
more info or order :
product information
Name :
Anti-FCGR1 [10.1]
Catalogue Number :
151026
Applications :
FACS IHC IF IP Fn
Antigen/Gene or Protein Targets :
Fc-gamma receptor 1 (FCGR1, CD64)
Synonyms :
Fc Fragment Of IgG Receptor Ia; Fc Gamma Receptor Ia; Fc-Gamma RIA; IGFR1; FCRI; Fc Gamma Receptor; CD64 Antigen; FCGR1; CD64; FCG1
Reactivity :
Human
Relevance :
Fc-gamma receptor 1 (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines. It is a marker of iflammation. It is involved in cancer and many chronic diseases (arthritis, multiple sclerosis, diabetic ulcers), but also in antibody-dependent cell-mediated cytotoxicity (ADCC), sepsis, automimmune disorders and periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. The 10.1 antibody blocks the Ig binding to FcR1 receptor.
Host :
Mouse
Immunogen :
Rheumatoid synovial fluid cells and fibronectin purified human monocytes.
Subclass :
IgG1
Positive Control :
Myeloid cell lines U937 and HL60
Molecular Weight (kDa) :
71
Myeloma Used :
Sp2/0-Ag14
Recommended Growing Conditions :
DMEM + 5% FCS
Strain :
Balb/c
Research Area :
Cancer, Immunology
more info or order :
company information
Ximbio
enquiries@ximbio.com
ximbio.com