antibody

PE-FineTest(R)594 Anti-Human CD107a Antibody(H4A3)

PE5-30046

20T/100T

266/646 USD

monoclonal

mouse

PE

H4A3

PE-FineTest(R)594 Anti-Human CD107a Antibody(H4A3)

Flow cytometry Antibodies

Mouse

Monoclonal

PE-FineTest(R)594

H4A3

20T/100T

266/646 USD

CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

LAMP-1LGP-120 Lysosome-Associated Membrane Protein 1 LAMP-1

Human CD107a/LAMP

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)