antibody

PE-Cy5 Anti-Mouse CD62L Antibody(MEL-14)

PC5-30084

50T/100T

120/178 USD

monoclonal

rat

PE-Cy5

MEL-14

PE-Cy5 Anti-Mouse CD62L Antibody(MEL-14)

Flow cytometry Antibodies

Rat

Monoclonal

PE-Cy5

MEL-14

50T/100T

120/178 USD

CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

CD62L CD62 antigen-like family member L L-selectin LAM-1 LECAM1 Lnhr Ly-22 Ly22 Lymph node homing receptor Sell

Mouse CD62L

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)