antibody

PE-Cy5 Anti-Human CD193/CCR3 Antibody(5E8)

PC5-30067

20T/100T

266/646 USD

monoclonal

mouse

PE-Cy5

5E8

PE-Cy5 Anti-Human CD193/CCR3 Antibody(5E8)

Flow cytometry Antibodies

Mouse

Monoclonal

PE-Cy5

5E8

20T/100T

266/646 USD

CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

MIP1-alpha receptor like-2eotaxin receptor C-C chemokine receptor type 3 CC CKR3 CCR CCR3

Human CD193/CCR3

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)