PE-Cy5 Anti-Mouse/Rat Foxp3 Antibody(FJK-16s) | Wuhan Fine Biotech Co.,Ltd. PC5-30055 product information

product summary

company name :

Wuhan Fine Biotech Co.,Ltd.

product type :

antibody

product name :

PE-Cy5 Anti-Mouse/Rat Foxp3 Antibody(FJK-16s)

catalog :

PC5-30055

quantity :

50T/100T

price :

368/646 USD

clonality :

monoclonal

host :

rat

conjugate :

PE-Cy5

clone name :

FJK-16s

reactivity :

mouse

application :

flow cytometry

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage

product information

Catalog Number :

PC5-30055

Product Name :

PE-Cy5 Anti-Mouse/Rat Foxp3 Antibody(FJK-16s)

Product Type :

Flow cytometry Antibodies

Host Species :

Rat

Clonality :

Monoclonal

Conjugation :

PE-Cy5

Clone Name :

FJK-16s

Size :

50T/100T

List Price(USD) :

368/646 USD

Background :

FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4 + /CD25 - cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.

ALTnames :

IPEXJM2ScurfinZinc finger protein JM2 Forkhead box protein P3

Specificity :

Mouse/Rat Foxp3

Uses :

Research use only

Application Summary :

Storage :

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage