antibody

PE-Cy5 Anti-Mouse CD80 Antibody(16-10A1)

PC5-30024

50T/100T

190/310 USD

monoclonal

hamsters

PE-Cy5

16-10A1

PE-Cy5 Anti-Mouse CD80 Antibody(16-10A1)

Flow cytometry Antibodies

Armenian Hamster

Monoclonal

PE-Cy5

16-10A1

50T/100T

190/310 USD

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Activation B7-1 antigen B7 Cd80 T-lymphocyte activation antigen CD80

Mouse CD80

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)