antibody

FineTest(R)Violet 540 Anti-Human CD16 Antibody(3G8)

FV540-30061

20T/100T

266/646 USD

monoclonal

mouse

nonconjugated

3G8

FineTest(R)Violet 540 Anti-Human CD16 Antibody(3G8)

Flow cytometry Antibodies

Mouse

Monoclonal

FineTest(R)Violet 540

3G8

20T/100T

266/646 USD

CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Fc gamma receptor Fc gamma receptor 3 Fc?RIII

Human CD16

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)