TNF-alpha Rabbit Polyclonal | Wuhan Fine Biotech Co.,Ltd. FNab08821 product information

product summary

company name :

Wuhan Fine Biotech Co.,Ltd.

product type :

antibody

product name :

TNF-alpha Rabbit Polyclonal

catalog :

FNab08821

quantity :

100 ug

price :

300USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat; 1:200; loading ...; fig 3	Li X, Ye Z, Guo Q, Wang E, Pan Y. PDTC ameliorates neuropathic pain by inhibiting microglial activation <em>via</em> blockage of the TNFα-CX3CR1 pathway. Eur J Histochem. 2021;65: pubmed publisher

product information

Catalog Number :

FNab08821

Product Name :

TNF-alpha Rabbit Polyclonal

Product Type :

Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100 ug

List Price :

300USD

Background :

TNF, as also known as TNF-alpha, or cachectin, is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is expressed as a 26 kDa membrane bound protein and is then cleaved by TNF-alpha converting enzyme (TACE) to release the soluble 17 kDa monomer, which forms homotrimers in circulation. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

ALTnames :

Cachectin antibody, DIF antibody, TNF antibody, TNF a antibody, TNF alpha antibody, TNFA antibody, TNFSF2 antibody, Tumor necrosis factor antibody,TNF-alpha Antibody

Product Description :

TNF-alpha antibody: Rabbit Polyclonal antibody to TNF-alpha

Immunogen :

tumor necrosis factor (TNF superfamily, member 2)

Specificity :

Human, Mouse ,Rat

Purity :

≥95% as determined by SDS-PAGE

Application Summary :

ELISA, IHC,WB

Storage :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage