antibody

PCNA Rabbit Polyclonal

FNab06215

100 ug

polyclonal

domestic rabbit

nonconjugated

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

PCNA Rabbit Polyclonal

Antibody

Rabbit

Polyclonal

Unconjugated

IgG

100 ug

Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3′-5′ exonuclease and 3′-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells. This antibody is a rabbit polyclonal antibody raised against an internal region of human PCNA.

PCNA Antibody

PCNA antibody: Rabbit Polyclonal antibody to PCNA

proliferating cell nuclear antigen

Human, Mouse ,Rat,Zebrafish

≥95% as determined by SDS-PAGE

ELISA, IF, IP, WB, IHC, FC

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)