P27; KIP1 Rabbit Polyclonal | Wuhan Fine Biotech Co.,Ltd. FNab06068 product information

product summary

company name :

Wuhan Fine Biotech Co.,Ltd.

product type :

antibody

product name :

P27; KIP1 Rabbit Polyclonal

catalog :

FNab06068

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage

product information

Catalog Number :

FNab06068

Product Name :

P27; KIP1 Rabbit Polyclonal

Product Type :

Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100 ug

Background :

CDKN1B, also named as P27 or KIP1, is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. P27 binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controlling cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Downregulation of P27 has been implicated in the progression of several malignancies, including lung cancer, hepatocellular carcinoma, salivary cancer, oral squamous cell carcinomas, and gastric cancer.

ALTnames :

P27; KIP1 Antibody

Product Description :

P27; KIP1 antibody: Rabbit Polyclonal antibody to P27; KIP1

Immunogen :

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Specificity :

Human, Mouse

Purity :

≥95% as determined by SDS-PAGE

Application Summary :

ELISA, WB, IP, IHC, IF

Storage :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)

more info or order :

Wuhan Fine Biotech Co.,Ltd. product webpage