product summary
Loading...
company name :
Wuhan Fine Biotech Co.,Ltd.
product type :
antibody
product name :
NR5A1 Rabbit Polyclonal
catalog :
FNab05847
quantity :
100 ug
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
more info or order :
product information
Catalog Number :
FNab05847
Product Name :
NR5A1 Rabbit Polyclonal
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100 ug
Background :
Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5′-YCAAGGYC-3′ and 5′-RRAGGTCA-3′ are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO- NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phosphatidylcholine (By similarity). Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3. Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
ALTnames :
AD4BP antibody, FTZF1 antibody, SF1 antibody,NR5A1 Antibody
Product Description :
NR5A1 antibody: Rabbit Polyclonal antibody to NR5A1
Immunogen :
nuclear receptor subfamily 5, group A, member 1
Specificity :
Human, Mouse ,Rat
Purity :
≥95% as determined by SDS-PAGE
Application Summary :
ELISA, WB, IHC, IP
Storage :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
more info or order :
company information
Wuhan Fine Biotech Co.,Ltd.
9 Bld, High-tech Medical Devices Park, No. 818 Gaoxin Ave.
East Lake High-tech Development Zone
Wuhan, Hubei
East Lake High-tech Development Zone
Wuhan, Hubei
sales1@fn-test.com
http://www.fn-test.com86-27-87384275
headquarters: China