antibody

IL33 Rabbit Polyclonal

FNab04271

100 ug

polyclonal

domestic rabbit

nonconjugated

western blot, ELISA, immunohistochemistry

IL33 Rabbit Polyclonal

Antibody

Rabbit

Polyclonal

Unconjugated

IgG

100 ug

Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an “alarmin”, that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528). In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin- associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets (PubMed:21734074). This form is rapidely lost upon angiogenic or proinflammatory activation (PubMed:18787100).

C9orf26 antibody, IL1F11 antibody, NFHEV antibody,IL33 Antibody

IL33 antibody: Rabbit Polyclonal antibody to IL33

interleukin 33

Human

≥95% as determined by SDS-PAGE

ELISA, IHC, WB

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)