antibody

CD22 Mouse Monoclonal

FNab01444

100 ug

monoclonal

mouse

nonconjugated

western blot, ELISA, immunohistochemistry

CD22 Mouse Monoclonal

Antibody

Mouse

Monoclonal

Unconjugated

IgG1

100 ug

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

SIGLEC2 antibody,CD22 Antibody

CD22 antibody: Mouse Monoclonal antibody to CD22

CD22 molecule

Human

≥95% as determined by SDS-PAGE

ELISA, WB, IHC

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)