antibody

CD14 Rabbit Polyclonal

FNab01426

100 ug

polyclonal

domestic rabbit

nonconjugated

western blot, ELISA, immunohistochemistry

CD14 Rabbit Polyclonal

Antibody

Rabbit

Polyclonal

Unconjugated

IgG

100 ug

Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (PubMed:23880187).

CD14 Antibody

CD14 antibody: Rabbit Polyclonal antibody to CD14

CD14 molecule

Human

≥95% as determined by SDS-PAGE

ELISA, IHC, WB

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)