Caspase 3, p17-specific Rabbit Polyclonal | Wuhan Fine Biotech Co.,Ltd. FNab01290 product information

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product summary

company name :

Wuhan Fine Biotech Co.,Ltd.

product type :

antibody

product name :

Caspase 3, p17-specific Rabbit Polyclonal

catalog :

FNab01290

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

product information

Catalog Number :

FNab01290

Product Name :

Caspase 3, p17-specific Rabbit Polyclonal

Product Type :

Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100 ug

Background :

Caspase 3, also named as CPP32, SCA-1 and Apopain, belongs to the peptidase C14A family. Caspase 3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp- -Gly-217’ bond. Caspase 3 cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. CASP3 is involved in the cleavage of huntingtin. The antibody can recognize p17 of caspase 3 specifically.

Immunogen :

caspase 3, apoptosis-related cysteine peptidase

Specificity :

Human, Mouse ,Rat

Purity :

≥95% as determined by SDS-PAGE

Application Summary :

ELISA, WB, FC, IHC, IF

Storage :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)