antibody

FineTest(R)700 Anti-Human CD80 Antibody(2D10)

F700-30041

20T/100T

280/646 USD

monoclonal

mouse

nonconjugated

2D10

FineTest(R)700 Anti-Human CD80 Antibody(2D10)

Flow cytometry Antibodies

Mouse

Monoclonal

FineTest(R)700

2D10

20T/100T

280/646 USD

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

B7BB1 B7-1 T-lymphocyte activation antigen CD80

Human CD80

Research use only

FC

PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8? for 12 months (Avoid repeated freeze / thaw cycles.)